QuestionsAnswered.net

What's Your Question?

## What Is a Case Study?

## Deep Dive into a Topic

## Study a Pattern

## Gather Evidence

## Present Findings

## Draw Conclusions

MORE FROM QUESTIONSANSWERED.NET

## Confidence Intervals

## C. Confidence Intervals for the Odds Ratio

return to top | previous page | next page

- Appendix D: Method for Determining the Confidence Interval Around the Odds Ratio
- Download Chapter PDF

## Jump to a Section

## Get Free Access Through Your Institution

Pop-up div successfully displayed.

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-.

## StatPearls [Internet].

Steven Tenny ; Mary R. Hoffman .

## Affiliations

Odds Ratio = (odds of the event in the exposed group) / (odds of the event in the non-exposed group)

First, we calculate the odds in the exposed group.

Next we calculate the odds for the non-exposed group.

Finally we can calculate the odds ratio.

Odds Ratio Confidence Interval

- Upper 95% CI = e ^ [ln(OR) + 1.96 sqrt(1/a + 1/b + 1/c + 1/d)]
- Lower 95% CI = e ^ [ln(OR) - 1.96 sqrt(1/a + 1/b + 1/c + 1/d)]

Confidence Interval Interpretation

Disclosure: Steven Tenny declares no relevant financial relationships with ineligible companies.

Disclosure: Mary Hoffman declares no relevant financial relationships with ineligible companies.

## In this Page

## Related information

## Similar articles in PubMed

- Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. [Cochrane Database Syst Rev. 2022] Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, et al. Cochrane Database Syst Rev. 2022 Feb 1; 2(2022). Epub 2022 Feb 1.
- Making sense of odds and odds ratios. [Obstet Gynecol. 2008] Making sense of odds and odds ratios. Grimes DA, Schulz KF. Obstet Gynecol. 2008 Feb; 111(2 Pt 1):423-6.
- [Roaming through methodology. XI. 'Odds' and so forth]. [Ned Tijdschr Geneeskd. 1998] [Roaming through methodology. XI. 'Odds' and so forth]. Scholten RJ. Ned Tijdschr Geneeskd. 1998 Nov 7; 142(45):2452-4.
- Review Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes. [Cochrane Database Syst Rev. 2005] Review Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes. Bakhai A, Hill RA, Dundar Y, Dickson R, Walley T. Cochrane Database Syst Rev. 2005 Jan 25; 2005(1):CD004588. Epub 2005 Jan 25.
- Review The relative merits of risk ratios and odds ratios. [Arch Pediatr Adolesc Med. 2009] Review The relative merits of risk ratios and odds ratios. Cummings P. Arch Pediatr Adolesc Med. 2009 May; 163(5):438-45.

## Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

National Library of Medicine 8600 Rockville Pike Bethesda, MD 20894

Web Policies FOIA HHS Vulnerability Disclosure

## Software for attributable risk and confidence interval estimation in case-control studies

- 1 Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Italy.
- PMID: 8689875
- DOI: 10.1006/cbmr.1996.0006

## Publication types

- Research Support, Non-U.S. Gov't
- Age Factors
- Alcohol Drinking / epidemiology
- Case-Control Studies*
- Confidence Intervals*
- Confounding Factors, Epidemiologic
- Esophageal Neoplasms / epidemiology
- Logistic Models
- Models, Statistical
- Probability
- Reproducibility of Results
- Risk Factors
- Smoking / epidemiology

## Comparison of approaches to estimate confidence intervals of post-test probabilities of diagnostic test results in a nested case-control study

BMC Medical Research Methodology volume 12 , Article number: 166 ( 2012 ) Cite this article

## Patient data

## Nested case–control samples

## Approaches to estimate the uncertainty of predictive values of a diagnostic test from a nested case–control study

## Statistical analysis

Analyses were performed with R version 2.6.0 [ 17 ].

Article CAS PubMed Google Scholar

Article PubMed PubMed Central Google Scholar

Article CAS PubMed PubMed Central Google Scholar

Ernster VL: Nested case–control studies. Prev Med. 1994, 23 (5): 587-590. 10.1006/pmed.1994.1093.

## Pre-publication history

## Author information

Bas van Zaane & Karel GM Moons

You can also search for this author in PubMed Google Scholar

## Corresponding author

Correspondence to Bas van Zaane .

## Additional information

The authors declare that they have no competing interests.

## Authors' contributions

## Authors’ original submitted files for images

Below are the links to the authors’ original submitted files for images.

## Authors’ original file for figure 1

## About this article

DOI : https://doi.org/10.1186/1471-2288-12-166

## Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

- Deep Vein Thrombosis
- Positive Predictive Value
- Negative Predictive Value
- Source Population
- Coverage Probability

## BMC Medical Research Methodology

- Submission enquiries: [email protected]
- General enquiries: [email protected]

## IMAGES

## VIDEO

## COMMENTS

A confidence interval indicates how uncertain a researcher is about an estimated range of values. A 99 percent confidence interval indicates that if the sampling procedure is repeated, there is a 99 percent chance that the true average actu...

When you’re performing research as part of your job or for a school assignment, you’ll probably come across case studies that help you to learn more about the topic at hand. But what is a case study and why are they helpful? Read on to lear...

Case studies are important because they help make something being discussed more realistic for both teachers and learners. Case studies help students to see that what they have learned is not purely theoretical but instead can serve to crea...

... computing a risk ratio, a risk difference (or rate ratios and rate differences), or, in the case of a case-control study, an odds ratio.

In case-control studies it is not possible to estimate a relative risk, because the denominators of the exposure groups are not known with a

How do you use a 95% confidence for the odds ratio to determine statistical significance at alpha = 0.05? Which of the following 95% confidence interval for

The prior chapter use risk ratios from cohort studies to quantify ... The 95% confidence interval for the ψ = e1.7299 ± (1.96)(0.1752)

An approximate 95% confidence interval (CI) around the point estimate of the odds ratio (OR) for an unmatched case–control study can be calculated using the

Calculating the 95% confidence interval for our previous hypothetical population we get:.

It is suited to analysis of the relationship between risk factors and disease in case-control studies with simple random sampling of controls, in terms of

Nested case–control studies become increasingly popular as they can be very ... The 95% confidence interval can simply be calculated as PPV

Quick review of the design of case –control studies. • Calculating Odds ratios. • 95% confidence interval for Odds ratios. • Relationship between odds ratio

The 95% confidence interval for the population value of R is then given as: e<>8782 t0 e12094 that is, from 2-41 to 3-35. UNMATCHED CASE-CONTROL STUDY.

Reading research, biostatistics--Risk factors and protective associations--Associated hypothesis tests-- USMLE biostats.